Milo Ventimiglia Milo joins the show. Chats about his new movie 'Pathology".
Hugh Jackman Hugh talks about his new movie "Deception"
Ashlee Simpson Find out more about Ashlee's new album and what she says about her engagement.
Nelly Find out more about Nelly's album "Brass Knuckles"
Gavin Rossdale Gavin talks about his upcoming solo album and tour
Britney Snow Britney and Ryan chat about "Prom Night"
Adam Levine Adam joins the show. Find out more about the Maroon 5 tour and new album.
Alicia Keys Alicia calls in. She a Ryan chat about her tour and her new role on MTV.
Chris Cornell Listen to Chris' opinion of David Cook's performance of "Billie Jean" on American Idol
Miranda Cosgrove Miranda and Ryan chat about her new show iCarly
Drake Bell Drake joins the show. Find out more about "Superhero Movie"
Leona Lewis Leona calls in. Talks about her new album "Spirit" and her journey through "The X Factor".
Thandie Newton Thandie drops by the studio. She and Ryan talk about her new movie "Run Fat Boy Run"
Jared Leto Find out more about Jared's new movie "Chapter 27" and how he prepared for the role.
Kate Bosworth Kate and Ryan chat about her new movie "21"
Mariah Carey Listen as Mariah talks about her "Saturday Night Live" performance. Find out what happens when Perez Hilton joins the conversation.
Ashton Kutcher Find out more about Ashton's new shows "Pop Fiction" and "Game Show in My Head".
Judd Apatow Judd and Ryan chat about "Drillbit Taylor"
Paul Mckenna Paul discusses his show on TLC "I Can Make You Thin"
Raven Symone Raven call in about her new movie "College Roadtrip"
Brett Ratner Brett and Ryan chat about Mariah Carey's new video and his upcoming project.
James McAvoy James talks about his new movie role
T R Knight T R knight joins the show
Ashley Simpson Ashley stops by. Find out more about her new album.
Brooke Shields Brooke joins Ryan to chat about "Lipstick Jungle"
Nigel Lythgoe Nigel stops by to chat about this season's American Idol.
Paramore Hayley calls in. Ever want to know who "Misery Business" is about? Listen here!
Enrique Iglesias Enrique stops by the studio. Download his interview here.
Kate Hudson Kate and Ryan talk "Fool's Gold"
Rachel Bilson Rachel talks about her new movie "Jumper"
Vince Vaughn Vince calls in about his "Wild West Comedy Show".
Ryan Sheckler Ryan stops by. Talks about his reality show and his charity fundraiser.
Hayden Christensen Hayden talks about his new movie "Jumper"
Avril Lavigne Check out Ryan's interview with Avril!
Eva Longoria Eva stops by and chats about her new movie.
Jenny McCarthy Jenny calls in about her new book.
Katherine Heigl Katherine Heigl and Ryan chat with us about her new movie "27 Dresses".
Mischa Barton Mischa talks about her new movie "Homecoming"
Alicia Keys Alicia calls in about her new album
The Girls Next Door The Girls chat with Ryan about the show.
Miley Cyrus Ryan chats with Miley
Jessica Alba Jessica and Ryan talk about her new movie "Awake"
Nicole Kidman Nicole calls in about her role in "The Golden Compass"
Sean Kingston Sean joins Ryan in the studio
Patrick Dempsy Patrick calls in about "Enchanted" and the writer's strike.
Natasha Bedingfield Natasha and Ryan chat about her new album
Guy Ritchie Guy talks about his new movie.
Chris Brown CB joins the show. Find out more about his success, the cd and movie.
Diddy Diddy's doing too much to summarize. Check out the interview here.
Lance Bass Lance stops by to talk about his new book.
Petra Nemcova Petra chats about her new calendar.
Rob Thomas Rob and Ryan chat about Matchbox Twenty and the upcoming tour
Jimmy Kimmel Jimmy talks about hosting the American Music Awards
Ice-T Ryan interviews Ice-T and Coco
Vince Vaughn Vince and Ryan chat about his new movie
BJ Novak BJ calls in about his many roles on "The Office"
Heidi Klum Find out how Heidi manages her many roles.
Julian McMahon Julian calls in about the success of "Nip Tuck"
Victoria Beckham Victoria stops by to talk about the Spice Girls reunion
Rihanna Rihanna and Ryan talk about he success of "Umbrella" and her new single "Hate That I Love You" with Ne-Yo.
Pete Wentz Pete calls in about the Fall Out Boy tour and their new single.
The Jonas Brothers The Jonas Brothers stop by to talk about their tour.
Eva Mendez Eva calls in about her new movie "We Own the Night"
J.R. Rotem J.R. talks to Ryan about his work on Britney's new album.
Molly Sims Molly talks to Ryan about Las Vegas
Ben Affleck Ben calls in about his new movie "Gone Baby Gone".
Ellen DeGeneres Ellen calls in about her show and her experiences with breast cancer.
Mel B. Mel discusses her experiences with "Dancing With the Stars"
Kim Kardashian Listen to the family talk about the new show "Keeping Up with the Kardashians"
Nicole Scherzinger Nicole and Ryan chat about her new album.
Kanye West Kanye calls in about having the #1 album in the country and his relationship with MTV
Tyra Banks Tyra talks about the new season of "America's Next Top Model".
Jamie Foxx Find out more about Jamie's new movie "The Kingdom".
Dwayne "The Rock" Johnson Why does Ryan call him the "Greatest American Hero"? Find out here. Ryan chats with "The Rock".
Dane Cook Dane describes his experience filming "Good Luck Chuck"
Gwen Stefani Find out more about the new No Doubt album
Good Charlotte Joel and Benji stop by the studio.
Jessica Alba Jessica calls in about "Good Luck Chuck"
Seth Green Ryan and Seth chat about "Robot Chicken"
Jordin Sparks Jordin and Ryan talk about her new single "Tattoo".
Donald Trump Find out what Donald's been up to.
David Beckham Chek out Ryan's interview with David Beckham
Daniel Radcliffe Interview with Daniel Radcliffe
50 Cent 50 stops by. Talks about his album Curtis and his competition with Kanye West.
Clive Owen Find out more about Shoot 'Em Up, Clive's new movie.
James Blunt James and Ryan talk about his upcoming album
Fergie Fergie stops by. Find out what she's been up to.
Christopher Mintz-Plasse Christopher calls in about "Superbad"
T.I. T.I. calls in from ATL. Find out more about T.I. vs T.I.P
Plain White T's Tom stops by. Talks about the inspiration behind "Hey There Delilah"
Mandy Moore Mandy calls in about her new movie "Dedication"
Jon Cryer Jon and Ryan talk about the Emmy's and "Two and a Half Men"
Jennifer Lopez Jenneifer talks about her album and upcoming tour with Marc Anthony.
Brett Ratner Find out more about how Brett got started and "Rush Hour 3"
Jonah Hill Jonah calls in about "Superbad"
Vanessa Hudgens Vanessa and Ryan talk "High School Musical 2"
Backstreet Boys The Backstreet Boys drop by. They talk about their new album and their fans.
Chris Tucker Chris calls in about "Rush Hour 3" and his recent travels
Seth Rogen Seth and Ryan talk about his new movie "Superbad" and some of his upcoming roles.
Whoopi Goldberg Whoopi talks about her new spot on "The View" and her morning radio show "Wake up With Whoopi"
Nick Cannon Nick Cannon stops by. Find out what he's been workng on.
Ken Paves Ken and Ryan chat about styling hair for some of our favorite celebs.
Ashton Kutcher Ashton calls in about his new MTV show Room 401.
Adam Sandler Find out what Adam's working on and more about "I Now Pronounce You Chuck and Larry"
Gavin Rossdale Find out more about Gavin's future music plans and his new movie "How to Rob a Bank"
Miley Cyrus Miley Cyrus calls in. Find out what Miley has to say about Daniel Radcliffe
Ivanka Trump Find out what projects Ivanka's involved in what's going on with "The Apprentice".
Amanda Bynes Amanda stops by to talk "Hairspray" with Ryan
Elisha Cuthbert Find out more about Elisha and her new movie "Captivity"
Sean Kingston Ryan Seacrest Interviews Sean Kingston.
Shea LeBouf Ryan Seacrest Interviews Shea LeBouf.
Rob Thomas Ryan Seacrest Interviews Rob Thomas.
Josh Duhamel Ryan Seacrest Interviews Josh Duhamel.
Jordin Sparks Jordin calls in. Listen to her reaction to the 'Lose Weight' comment from MeMe Roth
Lloyd Lloyd stops by. What does he have to say about Ciara? Find out here. Great interview!
Michael Buble Michael and Ryan chat about his tour, album and so much more.
Pamela Anderson Find out more about Pam's new show "The Beauty of Magic" and her kids reaction to "Borat".
Steve Carell Steve Carell calls in about "Evan Almighty"
Bruce Willis Bruce calls in about "Live Free Or Die Hard"
Kelly Clarkson Kelly and Ryan talk "My December" and so much more.
Samuel L. Jackson Sam calls in about "1408"
Nicole Richie Nicole Richie clears up rumors and talks about Paris and the new season of "The Simple Life"
Mandy Moore Mandy Moore stops by. Find out about her experience hosting AT40 and so much more.
Seth Rogan Find out more about "Knocked Up" and some of the casting ideas behind it.
Katherine Heigl Katherine calls in. Talks to Ryan about her role in Grey's Anatomy and his role in "Knocked Up"
Judd Apatow Judd and Leslie stop by to chat about "Knocked Up" and how the two of them met.
Emma Roberts Emma calls in. Find out about her driving test and her role in 'Nancy Drew"
Demi Moore Hear Demi talk about her new movie "Mr. Brooks".
Maroon 5 Find out the meaning behind "It Won't Be Soon Before Long". Adam from Maroon 5 calls in.
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